Food Scientist Awarded $2.65 Million NIH Grant for Diabetes Research

EAST GREENSBORO, NC (August 16, 2022) — Researcher at North Carolina Agricultural Technology State University awarded $2.65 million in grants over four years to advance his research on functional foods and human health received the money.

The grant was awarded to Dr. Shengmin Sang for a project aimed at studying dietary flavonoid biomarkers and targeting carbonyl stress to prevent type 2 diabetes. The grant was from the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health.

Sang is Distinguished Professor of Functional Foods and Human Health at A&T’s College of Agro-Environmental Sciences.his lab Center for Excellence in Post-Harvest Technology at the North Carolina Research Campus in Kannapolis. He will work on the latest project with his three collaborators at Harvard University.

“The main purpose of this study is to provide scientific evidence that eating flavonoid-rich foods can prevent the development of metabolic diseases.” As for why, I don’t know, I would like to know if these health foods can reduce the levels of toxic reactive carbonyl species in the body.

Sang has spent most of his career studying the relationship between functional foods (foods that provide more than basic energy and nutrition) and human health. Sang has focused primarily on flavonoids. Flavonoids are compounds commonly found in foods and drinks made from fruits, vegetables, and plants. Flavonoids have antioxidant properties that are thought to prevent toxins, inflammation, cardiovascular disease, kidney disease, diabetes and other chronic diseases. However, previous studies have been unable to demonstrate a clear link between flavonoids and chronic disease prevention in humans, as scientists have been unable to accurately measure flavonoid intake from the diet.

For this study, Sang and his team collected samples from human volunteers consuming green tea, soy milk, and blueberries (flavonoid-rich foods) and used a metabolomics approach to identify the top 15 dietary flavonoids. study biomarkers of They will also seek to determine whether flavonoids can reduce carbonyl stress caused by elevated levels of reactive carbonyl compounds in the body, which can lead to various chronic diseases. , to examine the relationship between these biomarkers and his risk of type 2 diabetes.

Sang received a Research Project Grant (R01), the NIH’s oldest and most competitive funding program for biomedical and health-related research. This award is her fourth NIH R01 grant for Sang. He used to drink tea, whole grains, ginger extract.

“This latest award is a testament to the important work Dr. Sun is doing to improve human health,” said Dr. Mohamed Ahmedna, Dean of CAES. “Dr. Sang’s latest work will help answer important questions about how the foods we eat can prevent a range of chronic diseases. This is an important study, NC A&T is grateful for his financial support from the NIH.”

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